Transamin (Cyklokapron)

Overview

What is Transamin (Cyklokapron)? 

Transamin, also known by its generic name tranexamic acid and its brand name Cyklokapron, is a medication that helps control or prevent excessive bleeding. It contains tranexamic acid, which is an antifibrinolytic agent that works by inhibiting the breakdown of blood clots.

Tranexamic acid, the active ingredient in Transamin, is a synthetic derivative of the amino acid lysine. It is produced in laboratories through a process of chemical synthesis. 

Global Name

Generic name: Tranexamic Acid
Brand names:  Cyklokapron and Lysteda

Usage

What is Transamin (Cyklokapron) used for? 

Transamin is used to treat or prevent excessive bleeding in various conditions, such as: 

• Heavy menstrual bleeding 
• Nosebleeds 
• After tooth extraction in patients with hemophilia 
• During and after surgery to reduce the need for blood transfusion 
• Hereditary angioedema 

How do you use Transamin (Cyklokapron)? 

Availability:

Transamin is available in tablet form, injectable solutions, and oral solutions.

Dosage information:

• The dose can vary based on the condition being treated. 
• For heavy menstrual bleeding, the typical dose is 1300 mg taken three times a day for up to four days. 
• For dental procedures in hemophilia patients, a typical dose is 10 mg per kg body weight, taken three to four times daily. 

Suitability: 

• Children: Suitable for children with dosage adjustments. 
• Adults: Suitable for adults. 
• Elderlies: Suitable for elderly patients with dosage adjustments if kidney function is impaired. 

Is there anyone who can’t take Transamin (Cyklokapron)? 

• Children: Not recommended for children under 18 for certain conditions; use with caution. 
• Adults: Most adults can take Transamin, but it should be used with caution in patients with kidney impairment. 
• Elderlies: Dosage adjustments may be necessary for elderly patients. 
• Pregnancy: Should only be used if the potential benefits justify the potential risks to the fetus. 
• Lactation: Caution is advised; consult a healthcare provider. 
• Allergies: Individuals with an allergy to tranexamic acid or any other component of the medication should not take Transamin. 

Warnings and Precautions:

Patients with a history of blood clots or thromboembolic disease should not take Transamin. Caution in patients with renal impairment (95% of the drug is excreted in urine).

Drug Interactions: 

Transamin should not be used with combination hormonal contraceptives due to the increased risk of blood clots. Not recommended to be administered more than 3 hours after a traumatic event with hemorrhage. 

Side Effects

Side effects can include nausea, vomiting, diarrhea, and the potential for blood clots.

Pharmacist Tips

Storage information:

• Store at room temperature, away from light and moisture.

• Do not use if the solution is discolored or contains particulate matter.
  
  
  

Availability

Where is Transamin (Cyklokapron) available in Hong Kong?

Transamin (Cyklokapron) is a prescription medication that can be prescribed by healthcare providers.

FAQs

How does Transamin work to prevent bleeding?

Transamin works by blocking plasminogen from binding to fibrin, preventing the breakdown of fibrin clots. 

Can I take Transamin for minor bleeding episodes?

Transamin is typically used for more significant bleeding episodes; consult a healthcare provider for minor bleeding.

Is it safe to drive or operate heavy machinery while taking Transamin?

Transamin may cause dizziness; avoid driving or operating heavy machinery until you know how it affects you.

How to use Transamin (Cyklokapron)?

Follow your healthcare provider's instructions. Take the tablets or solution by mouth, usually two to three times daily or as directed. The injectable form should be administered by a healthcare professional.