Diphenhydramine

Overview

What is Diphenhydramine? 

Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold, as well as for its sedative properties to induce sleep. 

Global Name

Generic name: Diphenhydramine
Brand name: Benadryl, Sominex, Nytol

Usage

What is Diphenhydramine used for? 

Diphenhydramine is used to alleviate allergic reactions, treat motion sickness, nausea, suppress cough (antitussive) and as a sleep aid. 

How do you use Diphenhydramine? 

Availability: 
This medication is available in tablet, liquid, and topical forms. 

Dosage information: 

• Adults: 25-50 mg every 4-6 hours for allergies; up to 50 mg at bedtime for sleep aid. 
• Children: Dosage varies by age and weight; consult with a pediatrician. 

Suitability: 

• Children: Yes, with pediatrician's approval. 
• Adults: Yes, as recommended. 
• Elderlies: Lower doses may be required. 
• Pregnancy: Not recommended unless prescribed. 
• Lactation: Not recommended without medical advice. 

Contraindications: 

• Allergies: To diphenhydramine or excipients in the formulation. 
• Medical Conditions: Asthma, glaucoma, heart disease, high blood pressure, thyroid disease, or enlarged prostate. 

Warnings: 
Diphenhydramine can cause marked drowsiness. Avoid alcohol, and use caution when driving or performing tasks requiring alertness. 

Interactions: 
Concurrent use with other sedatives or alcohol can increase drowsiness. Monoamine oxidase (MAO) inhibitors, an anti-depressant medication, can prolong and intensify the anticholinergic effects of antihistamines. 

Side Effects

Pharmacist Tips

• Storage: Keep in a cool, dry place away from children. 
• Alcohol: Avoid alcohol as it increases sedative effects. 
• Topical Use: Do not apply creams to large areas of the skin or open wounds. 
• Elderly Caution: Be particularly cautious in elderly patients due to increased risk of confusion and falls.

Availability

Where is Diphenhydramine available in Hong Kong?

 Diphenhydramine is an over-the-counter (OTC) medication that can be sold without a prescription. It is found in all chain drug stores, including Mannings and Watsons.

FAQs

Is Diphenhydramine available over-the-counter?

Yes, it is available OTC for both allergy relief and sleep aid.

Can Diphenhydramine be taken daily for allergies?

It can be taken daily, but long-term use should be under medical advice.

How quickly does Diphenhydramine take effect?

It typically begins to work within 30 minutes of ingestion.

How long does Diphenhydramine last?  

Diphenhydramine typically lasts between 4 to 6 hours, with the peak effects occurring within the first 1 to 3 hours after ingestion.